Discovery of 6,7-Dihydropyrazolo[1,5-a]pyrazin-4(5H)-one Derivatives as mGluR2 Negative Allosteric Modulators with In Vivo Activity in a Rodent’s Model of Cognition

Post time 2024-9-23 17:35:59

journal：Journal of Medicinal Chemistry

Authors：Sergio A. Alonso de Diego; María Lourdes Linares; Aránzazu García Molina; Ana Isabel de Lucas; Alcira del Cerro; Jose Manuel Alonso; Luc Ver Donck; Jose María Cid; Andrés A. Trabanco; Michiel Van Gool

Published date：2024-9-12

DOI：10.1021/acs.jmedchem.4c01227

PDF link：https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c01227

Article link：http://dx.doi.org/10.1021/acs.jmedchem.4c01227

Article Source：American Chemical Society (ACS)。

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Post time 2024-9-23 17:36:00

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[ACS] Discovery of 6,7-Dihydropyrazolo[1,5-a]pyrazin-4(5H)-one Derivatives as mGluR2 Negative Allosteric Modulators with In Vivo Activity in a Rodent’s Model of Cognition

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[ACS] Discovery of 6,7-Dihydropyrazolo[1,5-a]pyrazin-4(5H)-one Derivatives as mGluR2 Negative Allosteric Modulators with In Vivo Activity in a Rodent’s Model of Cognition Copy

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[ACS] Discovery of 6,7-Dihydropyrazolo[1,5-a]pyrazin-4(5H)-one Derivatives as mGluR2 Negative Allosteric Modulators with In Vivo Activity in a Rodent’s Model of Cognition